Oral Antivirals Show No Benefit in Hospital COVID-19 Care
Jun 26, 2025 · The addition of molnupiravir or nirmatrelvir-ritonavir to usual care does not reduce 28-day mortality or improve other clinical outcomes in patients hospitalized with COVID-19.
Most COVID-19 Drugs Fall Short, Meta-Analysis Confirms
Jul 10, 2025 · A meta-analysis of 187 trials shows that Paxlovid and remdesivir reduce the risk for hospitalization in patients with mild-to-moderate COVID-19 with moderate certainty.
Oral Antiviral Stops SARS-CoV-2 in its Tracks - Medscape
Mar 8, 2021 · A single pill of the investigational drug molnupiravir taken twice a day for 5 days eliminated SARS-CoV-2 from the nasopharynx of 49 participants.
What to Know About COVID Rebound - Medscape
Feb 21, 2024 · The CDC's Pragna Patel, MD, MPH, and Dallas Smith, PharmD, answer common questions on COVID-19 rebound cases and antiviral treatment.
Is anyone prescribing molnupiravir for outpatient COVID? : r
Dec 22, 2022 · Molnupiravir, even based on the clinical data that got it approved, is nearly a useless drug. Number needed to treat its high even pre vaccine, risk reduction is low, and it's …
First Pill for COVID-19 Could Be Ready by Year's End - Medscape
Mar 12, 2021 · New medications are in clinical trials and, if successful, will be ready to treat patients with COVID-19 by the end of the year.
First COVID Encounter: To Take Molnupiravir (Lagevrio) or Not?
Dec 2, 2023 · My doc handed me a script for Molnupiravir, also known as Lagevrio, which I've filled but now I'm sitting on the fence about actually taking it. In the meantime, I'm sticking with …
Nirmatrelvir Speeds Recovery, Cuts Symptoms in COVID-19
Aug 21, 2025 · Patients receiving nirmatrelvir/ritonavir experience a quicker resolution of COVID-19 symptoms and are less likely to have worsened symptoms than those receiving placebo, a …
New Data Dulls Enthusiasm for First Oral Treatment for Mild
Molnupiravir is the first oral medicine for non-hospitalised patients with mild-to-moderate COVID-19. It is currently being evaluated for inclusion in the World Health Organization's (WHO's ...
NICE Trims COVID-19 Therapeutics List for Continued NHS Use
The National Institute for Health and Care Excellence (NICE) has recommended three medications for continued NHS use in England for treating COVID-19.