Many of the proteins that calmodulin binds are unable to bind calcium themselves, and use calmodulin as a calcium sensor and signal transducer. Calmodulin can also make use of the …

Calmodulin acts as an intermediary protein that senses calcium levels and relays signals to various calcium-sensitive enzymes, ion channels and other proteins. Calmodulin is a small …

Calmodulin is a ubiquitous, highly conserved protein that plays a critical role in numerous essential cellular functions, including Ca 2+ transport, cell motility, cytoskeletal assembly, …

Calmodulin is a protein that binds to the intracellular face of GPCRs, such as the μ-opioid receptor, and helps in reducing GPCR signaling by affecting G-protein coupling.

Sep 9, 2024 · Calmodulin, a protein critically important for the regulation of all major cardiac ion channels, is the quintessential cellular calcium sensor and plays a key role in preserving …

Apr 6, 2025 · Calmodulin (CaM) is a calcium-modulated protein that plays a crucial role in mediating the effects of calcium ions in living systems. It is a calcium-binding protein found in …

Calmodulin belongs to a family of proteins along with troponin C, another essential calcium-binding protein involved in muscle contraction. Calmodulin is an essential protein; mutations in …

Calmodulin mediates the control of a large number of enzymes, ion channels, and other proteins by calcium. Together with CEP110 and centrin, calmodulin is also involved in the pathway that …

Jul 1, 2011 · We studied the reorientation of the two major domains of calmodulin and the flexibility of the tether. The simulations shed light on the time-dependent availability of various …

Feb 13, 2025 · Calmodulin is a calcium-dependent molecular switch, activated by the binding of four calcium ions to EF-hand motifs, resulting in the accessibility of previously hidden apolar …