Key points New evidence has led to a change in the way that some patients with amyotrophic lateral sclerosis (ALS) are classified and treated. Based on the findings of a landmark trial,[1][1] the drug ...

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Key points The health implications of exposures to the Alberta oil sands are underresearched, despite more than a decade of calls from Indigenous communities and researchers for further investigation.

Background: Consent forms have become too long and often do little to help people understand the risk elements of their participation in research, instead focusing on risk reduction for research ...

Key points Dried plasma is dehydrated, powdered human plasma. Once mixed with sterile water, the reconstituted plasma delivers essential coagulation factors necessary for hemostasis and supports ...

Key points More than a decade after the launch of Canada’s Strategy for Patient-Oriented Research (SPOR), patient engagement is increasingly expected across the health research ecosystem.

An 82-year-old woman with metastatic urothelial carcinoma and hepatic metastases was admitted to hospital for profound neutropenia and general clinical deterioration. She was referred to our ...

The first time a patient handed me a health report generated with artificial intelligence (AI), I paused in disbelief. It wasn’t the creatinine level that unsettled me — it was the conclusion at the ...

Heat waves are associated with a 9.7% increase in mental health–related hospital presentations, and mental illness is one of the strongest predictors of heat-related deaths (odds ratio 3.61, 95% ...

Falls are the leading cause of injury-related hospital admissions and deaths among older adults (aged ≥ 65 yr) About 30% of older adults report a fall each year, and about 20% experience a ...

Legionella is an atypical cause of community-acquired pneumonia that often presents with a prodrome of fever, malaise, fatigue, and occasionally diarrhea before respiratory symptoms. In patients with ...