Justin Herbert and the Chargers have quietly rattled off three straight wins, most recently tallying AFC victories over Tennessee and Pittsburgh. That, despite throwing out third- and even fourth-string linemen in front of Herbert amid injury emergencies.

The Jacksonville Jaguars can't afford any more injuries but they got a crucial one early against the Los Angeles Chargers.

Jacksonville Jaguars pass rusher Travon Walker suffered a knee injury and is questionable to return to the game against the Los Angeles Chargers. Walker limped off the field and was taken to the medical tent for further evaluation. He exited the tent and was listed as questionable to return with a knee injury.

Jacksonville Jaguars' star player Travis Hunter is out for the season after undergoing knee surgery. The wide receiver/defensive back sustained an LCL injury during practice and will miss the remainder of 2025,

Jacksonville Jaguars pass rusher Josh Hines-Allen has moved into sole ownership of the franchise record for sacks. Hines-Allen, who entered the game tied with Tony Brackens at 55 career sacks, set the record against the Los Angeles Chargers with a sack of quarterback Justin Herbert.

The Chargers are 3-point favorites, according to the latest Chargers vs. Jaguars odds. The over/under for total points scored is 43.5. The Chargers are -155 money line favorites (risk $155 to win $100),