NGS enables the in-depth analysis of the genome and the identification and investigation of disease-associated variants–especially when workflows include target enrichment, which focuses on specific ...

The advent of ultrahigh-throughput next-generation sequencing (NGS) offers an improved approach to endocrine molecular diagnostics. There are three basic paradigms in which this technology is usually ...

Immunotherapies, such as immune checkpoint inhibitors, have transformed the treatment of advanced stage cancers. Unlike chemotherapies that kill cancer cells, these drugs help the body’s immune system ...

Although whole-exome sequencing (WES) has its limitations, particularly with respect to secondary or incidental findings, it may still shine in routine clinical care, particularly if testing is ...

insights from industryRenyi HuaMaternal-Foetal Medicine & Prental Diagnosis SpecialistInternational Peace Maternity and Chilren's Hospital In this interview, NewsMedical speaks with Renyi Hua, ...

Optimized Detection of Unknown MET Exon 14 Skipping Mutations in Routine Testing for Patients With Non–Small-Cell Lung Cancer PMD and clonal hematopoiesis are both common in patients with AML in first ...

Transformed SCLC from EGFR-mutated LUAD shows a unique mutational profile, complicating treatment approaches and highlighting the need for tailored therapies. Whole exome sequencing revealed ...

Immunotherapies, such as immune checkpoint inhibitors, have transformed the treatment of advanced stage cancers. Unlike chemotherapies that kill cancer cells, these drugs help the body's immune system ...

BGI-Research and the Maternal and Child Health Hospital of Hubei Province (MCHH) published whole-genome sequencing research results in npj Genomic Medicine. These results have revealed the genomic ...