Arizona Cardinals vs. San Francisco 49ers NFL game: How to watch, kickoff time, TV channel and more

The Sunday afternoon Cardinals vs. 49ers game will kick off at 4:25 p.m. ET on FOX. (Out-of-market fans can catch the game on ...

Where to watch 49ers vs. Cardinals free livestream today (9/21/25) without Streameast

The San Francisco 49ers face the Arizona Cardinals on Sunday, Sept. 21, 2025 in Week 3 of the NFL season at State Farm ...