New research addresses a gap in understanding how ketamine's impact on individual neurons leads to pervasive and profound changes in brain network function. A World Health Organization Essential ...

Neuroscientists have identified the binding site of low-dose ketamine, providing critical insight into how the medication, often described as a wonder drug, alleviates symptoms of major depression in ...

A new study by Canadian researchers brings us one step closer to understanding the antidepressant effects of ketamine in sub-anesthetic doses. In mice, the researchers identified how two ...

Low-dose IV infusions of ketamine are safe and effective in treating chronic pain, a new study says. Ketamine infusions as ...

Activation of the body’s opioid system may be required for ketamine’s antidepressant effects, new research hinted. In a small study of adults with major depressive disorder, taking the opioid blocker ...

These images demonstrate the different binding sites in NMDA receptors that the UB team has discovered are responsible for ketamine’s distinct clinical effects, as an anesthetic at high doses and as ...