Major depressive disorder (MDD) is one of the leading causes of disability worldwide, and approximately 30% of patients develop treatment-resistant depression (TRD), a condition that does not respond ...

Researchers from Japan have uncovered direct evidence showing how ketamine exerts its rapid antidepressant effects in ...

For people antidepressants can’t help, ketamine changes the brain in ways we can now see In A Nutshell For the first time, researchers used a specialized brain scan to watch how ketamine alters a key ...

New research addresses a gap in understanding how ketamine's impact on individual neurons leads to pervasive and profound changes in brain network function. A World Health Organization Essential ...

A new brain-imaging study has revealed how ketamine produces its fast antidepressant effects in people with treatment-resistant depression. Researchers tracked changes in a critical brain receptor ...