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Reference-quality genome assembly created for widely used RPE-1 human cell line

A research team led by Professor Simona Giunta at the University of Rome La Sapienza has produced the first reference-quality ...

Spotting stealth multiplets for better single-cell experiment design

Single-cell RNA sequencing (scRNA-seq) has revolutionized modern biology, allowing scientists to study the expression of ...
Labroots

Clinical applications of Sanger sequencing and fragment analysis via capillary electrophoresis

Due to its high accuracy and fast, simple workflow, capillary electrophoresis (CE) is a foundational technology for clinical applications. CE is an invaluable tool used to detect genetic var ...
Scientific Research Publishing

Hiraishi, A. (1992) Direct Automated Sequencing of 16S rDNA Amplified by Polymerase Chain Reaction from Bacterial Cultures without DNA Purification. Letters in Applied ...

ABSTRACT: Background: The yeast Saccharomyces cerevisiae plays a pivotal role in fermentation industries, yet its ecological behavior and methods for effective isolation from natural environments, ...
IEEE

Differentiation of Gut Microbiome Profiles Between Healthy and IBD Individuals Using 16S rRNA Sequencing and AI-Enhanced Analysis: Insights from Indian Cohorts

Abstract: Gut microbiome plays a major role in human health, and its dysbiosis is associated with diseases i.e. inflammatory bowel disease (IBD). This study investigates microbial differences between ...
eLife

Ribosomal RNA synthesis by RNA polymerase I is regulated by premature termination of transcription

This manuscript characterizes a mutated clone of RNA polymerase I in yeast, referred to as SuperPol, to understand the mechanisms of RNA polymerase I elongation and termination. The authors present ...
Frontiers

Combined metabolomics and 16S rDNA sequence analyses of the gut microbiome reveal the action mechanism of Fructus Akebiae against hepatic fibrosis

Objectives: To explore the mechanism underlying the effect of Fructus Akebiae (FAE) against hepatic fibrosis in mice through combined network pharmacology, liver metabolomics, and 16S rDNA analyses of ...
JSTOR Daily

Remarkable variation of ribosomal DNA organization and copy number in gnetophytes, a distinct lineage of gymnosperms

IntroductionGnetophytes, comprising the genera Ephedra, Gnetum and Welwitschia, are an understudied, enigmatic lineage of gymnosperms with a controversial phylogenetic relationship to other seed ...
Frontiers

Microbiota in Human Periodontal Abscess Revealed by 16S rDNA Sequencing

Periodontal abscess is an acute exacerbation of chronic periodontitis, exhibiting clinical symptoms of swelling and severe pain in the gingival margin. It is defined as a localized suppurative lesion ...