Researchers from the Department of Biomedical Engineering at UNIST and the Center for Genomic Integrity at the Institute for Basic Science (IBS) have announced an advance in cancer gene therapy. Their ...

Scientists have turned an old idea on its head. A new paper reports that stretches of so-called “junk DNA” can help injured ...

While scientists are amassing a fair amount of data regarding our gut microbiomes, the oral microbiome is a bit of a new ...

A new scientific review frames exercise as a geroprotector that slows aging and can even turn back your epigenetic clock.

Reporting in Nature, scientists have identified a novel process that protects the ends of chromosomes from incorrectly applied DNA repair.. | Cell And Molecular Biology ...

Researchers have uncovered a previously unknown mechanism that safeguards the chromosome ends from being mistakenly repaired by the cell. While DNA repair is vital for survival, attempts to repair the ...

Researchers have uncovered a previously unknown mechanism that safeguards the chromosome ends from being mistakenly repaired ...

Abstract Background and Purpose —Ku70 and Ku86, multifunctional DNA repair proteins, bind to broken DNA ends, including double-strand breaks, and trigger a DNA repair pathway. To investigate the ...

Not all DNA looks like the familiar double helix. Sometimes, parts of our genetic code fold into unusual shapes under certain conditions. One such structure known as a G-quadruplex (G4) looks like a ...

This first-in-the-world approach harnesses autophagy to shift DNA repair toward homologous recombination, boosting precision editing efficiency up to threefold. Dr. Hye Jin Nam’s team at the Korea ...

Our DNA is comprised of four bases — cytosine (C), thymine (T), guanine (G) and adenosine (A), arranged in a double-helix structure. (cr: Pakawadee Wongjinda / iStock) You may have seen it in the news ...

Researchers developed a biomimetic nanovesicle that crosses the blood-brain barrier, degrades DNA repair proteins, and restores temozolomide sensitivity in glioblastoma. (Nanowerk Spotlight) ...