Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, providing insights into its DNA recognition and cleavage mechanisms. The ...

To protect themselves against viral infection, bacteria often use CRISPR-Cas systems to identify and destroy an invading virus’s genetic material. But viruses aren’t helpless and can deploy ...

Overview of CRISPR/Cas system-based tumor molecular diagnostic strategies, including variant gene, protein, and liquid biopsy marker assays and in situ molecular analysis. The CRISPR/Cas system, known ...

The recent publication in Science by Mogila, Tamulaitiene et al. represents a continuation of the successful scientific research conducted by Gintautas Tamulaitis' group. In this study, the Vilnius ...

A microscopic discovery will not only enable scientists to understand the microbial world around us but could also provide a new way to control CRISPR-Cas biotechnologies. An international team of ...

The lack of efficient delivery methods is a major barrier to clustered regularly interspaced short palindromic repeats/CRISPR-associated protein (CRISPR/Cas)-mediated genome editing in many plant ...

The discovery of CRISPR-Cas gene editing technology has revolutionized biological research, providing new insights and opportunities for the advancement of several industries. However, the ...

Researchers have discovered a handful of new CRISPR-Cas systems that could add to the capabilities of the already transformational gene editing and DNA manipulation toolbox. Of the new recruits, one ...

The cryogenic electron microscope structure of the A4p-activated (green) CalpL protein filament (violet) from Candidatus Cloacimonas acidaminovorans (PDB ID: 9EYJ). CRISPR-Cas systems help to protect ...

The colonies of Escherichia coli sitting in this petri dish become pathogenic when they carry Shiga toxin genes. Credit: Shutterstock “We’re essentially converting a pathogenic strain into a ...