Turning genes on and off is like flipping a light switch, controlling whether genes in a cell are active. When a gene is ...

The trial's results will be pivotal in determining the therapy’s pharmacological profile and anticoagulant effects.

ZUG, Switzerland and BOSTON and SAN DIEGO and SHANGHAI, Sept (GLOBE NEWSWIRE) -- CRISPR Therapeutics (NASDAQ: CRSP), a ...

Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, providing insights into its DNA recognition and cleavage mechanisms. The ...

In nature, the best-known CRISPR system, CRISPR-Cas9, cuts any RNA or DNA it recognizes as foreign, and thereby protects bacteria from viral attacks. Another CRISPR system, one that is relatively ...

(Nanowerk News) The CRISPR-Cas gene scissors offer a wide range of potential applications, from the treatment of genetic diseases to antiviral therapies and diagnostics. However, to safely harness ...

CRISPR/Cas9 is a gene editing tool that has revolutionized biomedical research and led to the first FDA-approved CRISPR-based gene therapy. However, until now, the precise mechanism of exactly how ...

A research team led by Prof. Wang Yanli from the Institute of Biophysics of the Chinese Academy of Sciences has revealed the ...

CRISPR-Cas is an adaptive immune system of prokaryotes (bacteria and archaea). Apart from protecting its host against invading viruses, alternative biological functions of CRISPR-Cas have also been ...

The test can be administered on a mouth swab instead of sputum and doesn’t require lab facilities ...

The cryogenic electron microscope structure of the A4p-activated (green) CalpL protein filament (violet) from Candidatus Cloacimonas acidaminovorans (PDB ID: 9EYJ). CRISPR-Cas systems help to protect ...

Researchers engineered and screened dozens of base editors to precisely target a single mutation without editing other portions of the DNA.