Human papillomavirus (HPV) is the primary cause of virus-associated cancers, especially cervical and head and neck cancers. A ...

The 2020 Nobel Prize in Chemistry was awarded for the development of CRISPR/Cas9, a method also known as "gene scissors," ...

The study will interest researchers studying genome organisation in mitosis. Genomes assume a complex 3D architecture in the interphase cell nucleus. Yet, the molecular mechanisms that determine ...

Researchers engineered and screened dozens of base editors to precisely target a single mutation without editing other portions of the DNA.

More than a decade ago, scientists harnessed a bacterial molecular machine that identifies and cuts specific sections of DNA, ...

Autophagy—meaning "self-eating" in Greek—is a fundamental cellular mechanism that preserves cell health by recycling and degrading worn-out or dysfunctional components. Serving as an essential ...

A team of scientists at the Garvan Institute of Medical Research has discovered that inactivation of a stress pathway makes ER+ breast cancer cells ignore stress signals, allowing them to evade ...

Cas13a consists of two lobes—the recognition (REC) and nuclease (NUC) domains—and is guided by a crRNA (50–58 nt) comprising a direct repeat sequence followed by a spacer region. Under the canonical ...

CRISPR has taken the bioengineering world by storm since its first introduction. From treating sickle cell diseases to creating disease-resistant crops, the technology continues to boast success on ...