Northwestern scientists have developed a new nanostructure that supercharges CRISPR’s ability to safely and efficiently enter cells, potentially unlocking its full power to treat genetic diseases. By ...

The new system developed by Professor Chad Mirkin delivers CRISPR machinery more safely and effectively into cells.

Researchers have unveiled a new type of nanostructure that dramatically improves CRISPR delivery. Called lipid nanoparticle ...

Engineered bacteria reprogram tumor macrophages and direct copper into cancer cells, triggering cell death and systemic immunity without damaging healthy tissue.

More than a decade ago, scientists harnessed a bacterial molecular machine that identifies and cuts specific sections of DNA, ...

"Another strategy is to remove cells from the body, inject the CRISPR components and then put the cells back in. As you can imagine, that's extremely inefficient and impractical." A DNA-wrapped taxi ...

Scientists study a molecular machine that moves jumping genes in DNA, paving the way for a new gene editing tool beyond ...

For next steps, they are transitioning from liver spheroids to lab mice, and they're using nanoparticle delivery systems that introduce CRISPR gene-editing components directly into liver cells. Such a ...

Autophagy—meaning "self-eating" in Greek—is a fundamental cellular mechanism that preserves cell health by recycling and degrading worn-out or dysfunctional components. Serving as an essential ...

CRISPR gene-edited cell therapy improves quality of life in patients with transfusion-dependent beta thalassemia, research suggests.

With the power to rewrite the genetic code underlying countless diseases, CRISPR holds immense promise to revolutionize ...