RALEIGH – In a new study, North Carolina State University researchers characterize a range of molecular tools to rewrite – not just edit – large chunks of an organism’s DNA, based on CRISPR-Cas ...

Researchers engineered and screened dozens of base editors to precisely target a single mutation without editing other portions of the DNA.

Scientists have revealed how Fanzor2's divergence from bacterial ancestors may make it a useful tool for future genomic engineering endeavors. A revolution in biomedicine is currently underway, driven ...

Overview of CRISPR/Cas system-based tumor molecular diagnostic strategies, including variant gene, protein, and liquid biopsy marker assays and in situ molecular analysis. The CRISPR/Cas system, known ...

Zoom in of the mechanism: The RNA binding (in blue) flips the switch of the CRISPR-Cas system (in green), which activates its cutting mechanism. Disclaimer: AAAS and EurekAlert! are not responsible ...

The CRISPR-Cas (Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) and its associated protein (Cas9) system is a genome-editing technology that holds the potential to alleviate multiple ...

The lack of efficient delivery methods is a major barrier to clustered regularly interspaced short palindromic repeats/CRISPR-associated protein (CRISPR/Cas)-mediated genome editing in many plant ...

By Michelle Yang Researchers from Mie University in Japan used the gene editing tool CRISPR to remove the extra chromosome 21, the copy responsible for Down syndrome. Courtesy of digitale.de via ...