New York Giants vs San Francisco 49ers
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The 49ers travel to New York with a game plan that probably looks like the Atlanta game: run and run some more.
Ferrell and trade acquisition Keion White will be the new blood on the 49ers defensive line, moves that were made even more necessary with the 49ers’ placing defensive lineman Yetur Gross-Matos on injured reserve, meaning he will miss at least the next four games. The 49ers (5-3) face the Giants (2-6) Sunday at MetLife Stadium. (CBS, 10 a.m.)
The San Francisco 49ers face the New York Giants needing a win to rally amid another season threatening to be derailed by injuries. Here's what our NFL coverage team expects.
New York Giants linebacker Kayvon Thibodeaux (5) runs out of the tunnel during a Thursday Night Football game between the New York Giants and the Philadelphia Eagles at MetLife Stadium in East Rutherford on Oct. 9, 2025. / Julian Leshay Guadalupe/NorthJersey.com / USA TODAY NETWORK via Imagn Images
San Francisco 49ers QB Brock Purdy isn't all the way back from his "annoying" toe injury, but he will be available off the bench behind Mac Jones against the New York Giants on Sunday.