Kyle Shanahan's San Francisco 49ers will face off against a familiar foe on Sunday when they face the Houston Texans. DeMeco ...

Kickoff from NRG Stadium is set for 1 p.m. ET, and the Texans are 1.5-point favorites, according to the latest 49ers vs.

The San Francisco 49ers are used to playing shorthanded, but this week they will also face a foe that is coming in without ...

San Francisco's Christian McCaffrey and George Kittle pose challenges for Houston's defense, and 49ers' pass rush will be key ...

The New England Patriots D/ST continues to rank as a high-end fantasy option heading into another favorable matchup against the Cleveland Browns in Week 8. New England's defense has improved this year ...

Looking for a best bet for Sunday’s NFL action? You’ve come to the right place, as the SI Betting team has been making ...

Week 8 of the 2025 NFL season is upon us. Each week, I’ll look at the AFC South matchups and give you a couple of bold ...

Each week, we’re going to try and be better. To some degree, we had success with our NFC West Bold Predictions in Week 7. Of ...

The Seattle Seahawks are just seven points from a perfect record, but they feel there's another gear to hit with key ...

49ers 24, Texans 16: San Francisco may be without defensive pillars Nick Bosa and Fred Warner, but the Houston offense has ...

Witness rising stars and established anchors collide. These defensive playmakers will dictate the outcome when 49ers face ...

Grant Cohn and Tom Walsh discuss what the San Francisco 49ers defense needs to do to shut down the Houston Texans offense.