The EMBO Journal

ADAM10 and ADAM17 promote SARS‐CoV‐2 cell entry and spike protein‐mediated lung cell fusion

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The ...
The EMBO Journal

Genetically modified macrophages accelerate myelin repair

Preventing neurodegeneration‐associated disability progression in patients with multiple sclerosis (MS) remains an unmet therapeutic need. As remyelination prevents axonal degeneration, promoting this ...
The EMBO Journal

Distinct transcription kinetics of pluripotent cell states

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Mouse embryonic stem cells (mESCs) can adopt ...
The EMBO Journal

New precision medicine avenues to the prevention of Alzheimer’s disease from insights into the structure and function of γ-secretases

Two phase-III clinical trials with anti-amyloid peptide antibodies have met their primary goal, i.e. slowing of Alzheimer’s disease (AD) progression. However, antibody therapy may not be the optimal ...
The EMBO Journal

Predictability of the community‐function landscape in wine yeast ecosystems

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Predictively linking taxonomic composition and ...
The EMBO Journal

Role and mechanism of PVN–sympathetic–adipose circuit in depression and insulin resistance induced by chronic stress

Chronic stress induces depression and insulin resistance, between which there is a bidirectional relationship. However, the mechanisms underlying this comorbidity remain unclear. White adipose tissue ...
The EMBO Journal

Dynamin 1xA interacts with Endophilin A1 via its spliced long C-terminus for ultrafast endocytosis

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Dynamin 1 mediates fission of endocytic ...
The EMBO Journal

Perspective: a stirring role for metabolism in cells

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Based on recent findings indicating that ...
The EMBO Journal

Piccolino is required for ribbon architecture at cochlear inner hair cell synapses and for hearing

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Piccolino regulates ribbon morphology as well ...
The EMBO Journal

Graft conditioning with fluticasone propionate reduces graft‐versus‐host disease upon allogeneic hematopoietic cell transplantation in mice

Hematopoietic cell transplantation (HCT) treats many blood conditions but remains underused due to complications such as graft‐versus‐host disease (GvHD). In GvHD, donor immune cells attack the ...
The EMBO Journal

Downregulation of stromal syntenin sustains AML development

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The crosstalk between cancer and stromal cells ...
The EMBO Journal

New plastids, old proteins: repeated endosymbiotic acquisitions in kareniacean dinoflagellates

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Kareniacean plastids are distinct from those ...