The Astros look to rebound and avoid a sweep as they square off against the Marines in Game 3. Here are all the details about the game.

Christian Walker, in the middle of a rough homestand, was out of the lineup in favor of switch hitter Victor Caratini.

For the second straight game, the Houston Astros fell to the Seattle Mariners, this time by a score of 6-4 on Saturday at Daikin Park.

CBS Sports brings you live coverage, scoring, expert picks and stats for the MLB matchup between Seattle Mariners and Houston Astros on September 21, 2025

The Astros are now two games behind Seattle, which has the tiebreaker, and also fell behind Cleveland in the AL wild-card race.

They know how raucous and roaring this venue can be because they’ve lived through it, painstakingly through some of their most gut-punch losses over the past decade. Which made the silence that the Mariners evoked throughout Friday at Daikin Park that much more surreal.