The investigational drug tonlamarsen—which is designed to lower blood pressure by reducing the production of angiotensinogen, ...

While tonlamarsen missed one of two co-primary endpoints, Kardigan says the drug has shown a clinically meaningful effect on blood pressure, supporting advancement into Phase 2b.

In a phase 2 trial of a novel antihypertensive agent, multiple doses lowered plasma angiotensinogen to a greater extent than a single dose, but did not provide further blood pressure lowering, ...

Home-delivered groceries tailored to the low-sodium Dietary Approaches to Stop Hypertension diet improved BP among Black adults already being treated for hypertension, according to results from the ...

The program didn’t have a big impact on BP, but there were lessons for future attempts to address these health disparities.

A study from researchers at The University of Texas at El Paso shows that just six weeks of boxing training can significantly reduce blood pressure and improve blood vessel function in young adults ...

The investigational drug tonlamarsen—which is designed to lower blood pressure by reducing the production of angiotensinogen, a protein that turns into the hormone that regulates blood pressure—caused ...

SOUTH SAN FRANCISCO, Calif., & PRINCETON, N.J., March 28, 2026--Kardigan announced results from KARDINAL, a Phase 2 clinical trial evaluating the effects of tonlamarsen in patients with uncontrolled ...

At least 45% of global dementia risk is related to lifestyle factors that we have some control over,” one neuroscientist told ...

Blood pressure is one of the most common health checks in the world. Many people have had their blood pressure measured at a ...

Health care now favors everyday tracking rather than occasional checkups. Blood pressure (BP) is a key metric to show your ...

Pulse wave velocity, calculated from age and blood pressure changes, was associated with significant dementia risk in a post ...