A research team led by scientists from the Helmholtz Institute for RNA-based Infection Research (HIRI) has introduced a new ...

Maria Jasin, PhD, whose research on DNA repair has transformed our understanding of cancers, has been selected as the 2025 recipient of the Greengard Prize.

Jasin's fundamental research on repair of damaged DNA in cells has transformed our understanding of cancers linked to ...

Using optical tweezers, researchers at National Taiwan University have observed individual binding events in real time, offering new insights into the molecular regulation of homologous recombination.

PCAF (p300-associated factor), a major histone acetyltransferase, is involved in many metabolic and pathogenic diseases. Here, we reveal a novel function of PCAF in homologous recombination repair (HR ...

NEW YORK – The Association for Molecular Pathology on Tuesday published best practice recommendations for the design and validation of clinical tests for homologous recombination deficiency. The ...

FDA approves updated labeling for Talzenna plus Xtandi in men with HRR gene-mutated metastatic prostate cancer, showing a 14-month survival benefit. The U.S. Food and Drug Administration (FDA) ...

Please provide your email address to receive an email when new articles are posted on . Adding niraparib to abiraterone acetate and prednisone lowered risk for cancer growth by 37% among certain ...

CHICAGO – Johnson & Johnson has garnered fresh data that Akeega (niraparib/abiraterone acetate), a dual-action tablet comprising a PARP inhibitor and anti-hormone therapy, has promising activity as a ...

Background Alterations in BRCA1/2 (BRCA) and other homologous recombination repair (HRR) genes have a negative impact on outcomes in patients with metastatic castration-resistant prostate cancer ...

Identifying BRCAness in tumors, even in the absence of BRCA mutations, broadens the reach of targeted therapies, supporting more individualized and effective cancer treatment approaches. BRCAness ...