A newly developed mouse model enables real-time visualization of RNA Polymerase II (RNAP2) during DNA transcription, as ...

Boosting levels of a certain molecule that declines with age was found to restore memory and brain function in Alzheimer’s ...

Neurodegenerative diseases, such as Alzheimer's disease and dementia, are medical conditions that entail the progressive loss ...

Acetylation of lysine residues in the tail domain of histone H3 is well characterized, but lysine residues in the histone globular domain are also acetylated. Histone modifications in globular domain ...

RNA-based therapeutics are transforming medicine, but scaling production efficiently remains a challenge, particularly the ...

The work also links the enzyme's activity to multiple diseases, including cancer, for example, through the cell-surface ...

The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme's "tail" called phosphorylation patterns.

Researchers from the University of Eastern Finland and Aalto University have developed a computational framework called ...

This cover highlights the article A novel human fetal lung-derived alveolar organoid model reveals mechanisms of surfactant protein C maturation relevant to interstitial lung diseasee by Kyungtae Lim, ...

The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme's ...