Major depressive disorder (MDD) is one of the leading causes of disability worldwide, and approximately 30% of patients develop treatment-resistant depression (TRD), a condition that does not respond ...

Many proteins have a complex architecture that enables biological functions. Molecules can bind to specific sites on a protein and alter its function. A team at HZB has now investigated the Nsp1 ...

Researchers from Japan have uncovered direct evidence showing how ketamine exerts its rapid antidepressant effects in ...

Many proteins have a complex architecture that enables biological functions. Molecules can bind to specific sites on a ...

Discover a new low-dose, inexpensive, at-home treatment for depression that is revolutionizing the treatment of neuropsychiatric disorders.

Whether a smartphone battery lasts longer or a new drug can be developed to treat incurable diseases depends on how stably the atoms constituting the material are bonded. The core of molecular design ...

UVA Comprehensive Cancer Center scientists have identified a molecule that blocks the gene responsible for glioblastoma, raising hopes that the molecule could become a much-needed new treatment for ...

Many Texans who live with depression, anxiety, chronic pain, or PTSD have found some relief from treatment with the psychotropic drug ketamine. But lately, Texas regulators have been raising concerns ...

Abstract: Accurate extraction of molecular representations is a critical step in the drug discovery process. In recent years, significant progress has been made in molecular representation learning ...

Among critically ill adults undergoing tracheal intubation, ketamine for anesthesia did not result in a significantly lower incidence of in-hospital death by day 28 compared with etomidate. In ...