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The giant DNA loops were discovered through a careful study of saliva samples from 56 volunteers, with further tests ...
CTCF binding promotes chromatin-nuclear speckle interactions and gene activation after DNA demethylation, yet its binding and looping patterns are unaffected by speckle depletion.
Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA – its genome – and segregate it equally ...
As the cell proceeds through the stages of cell division (from left to right: interphase, prometaphase, metaphase, and anaphase), chromosomes become progressively more compact through a combination of ...
Scientists from the Kavli Institute of Delft University of Technology and the IMP Vienna Biocenter discovered a new property of the molecular motors that shape our chromosomes. While six years ago ...
The work reveals a previously unrecognized mechanism in the viral life cycle and highlights a potential vulnerability that ...
Scientists from the Kavli Institute of Delft University of Technology and the IMP Vienna Biocenter discovered a new property of the molecular motors that shape our chromosomes. While six years ago ...
For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process can lead to cell death or diseases like cancer. A new study has shown how ...