ChIP-seq, short for chromatin immunoprecipitation sequencing, combines chromatin immunoprecipitation with real-time next generation sequencing to identify genomic binding sites that proteins such as ...

The biomedical sciences have been transformed by the breakthrough of next-generation sequencing and derived techniques, such as ChIP-seq 1,2,3. Efficient use of such large-scale genomic data generated ...

Chromatin immunoprecipitation followed by sequencing (ChIP–seq) can be used to map DNA-binding proteins and histone modifications in a genome-wide manner at base-pair resolution. ChIP–seq offers ...

One of the major tasks in present-day biology is to map the chromosomal positions of nucleosomes, TFs, chromatin remodeling enzymes, histone modifications, polymerases and chaperones. Genome-wide ...

Chromatin immunoprecipitation (ChIP) is conceptually a simple method. Briefly, formaldehyde is used to crosslink DNA binding proteins to DNA. Sonication is then used to shear the DNA into small ...

Primate cross-species analysis of interactions between transposable elements and KRAB-ZNF genes with the new TEKRABber tool highlights human-specific interactions with potential relevance to Alzheimer ...