Claims that HIV has been permanently eradicated from people living with the virus are false. More research, refined delivery ...

Human papillomavirus (HPV) is the primary cause of virus-associated cancers, especially cervical and head and neck cancers. A ...

The 2020 Nobel Prize in Chemistry was awarded for the development of CRISPR/Cas9, a method also known as "gene scissors," ...

The study will interest researchers studying genome organisation in mitosis. Genomes assume a complex 3D architecture in the interphase cell nucleus. Yet, the molecular mechanisms that determine ...

Researchers engineered and screened dozens of base editors to precisely target a single mutation without editing other portions of the DNA.

More than a decade ago, scientists harnessed a bacterial molecular machine that identifies and cuts specific sections of DNA, ...

CRISPR has the power to correct genetic mutations, but current delivery methods are either unsafe or inefficient, keeping the technology from reaching its full medical potential. With the power to ...

Autophagy—meaning "self-eating" in Greek—is a fundamental cellular mechanism that preserves cell health by recycling and degrading worn-out or dysfunctional components. Serving as an essential ...

A team of scientists at the Garvan Institute of Medical Research has discovered that inactivation of a stress pathway makes ER+ breast cancer cells ignore stress signals, allowing them to evade ...

A new generation of CRISPR technology developed at UNSW Sydney offers a safer path to treating genetic diseases like sickle cell, while also proving beyond doubt that chemical tags on DNA—often ...

Cas13a consists of two lobes—the recognition (REC) and nuclease (NUC) domains—and is guided by a crRNA (50–58 nt) comprising a direct repeat sequence followed by a spacer region. Under the canonical ...