A mind-boggling stat highlights the San Francisco 49ers’ brutal injury luck under coach Kyle Shanahan since 2017.

Highlights from the Week 8 matchup between the San Francisco 49ers and the Houston Texans during the 2025 NFL season.

San Francisco 49ers' George Kittle made an outrageous touchdown catch, trimming the Houston Texans’ lead.

It was a fitting end for the 49ers. Jones took a shot to the end zone, targeting Jauan Jennings on the final play before the two-minute warning. His throw was intercepted by Texans cornerback Kamari ...

ChristianMcCaffrey, #49ers, #NFLHighlights49ers RB Christian McCaffrey 129 Yards, 2 TDs, 72 Receiving Yards Makes NFL History ...

Down 16-0, the 49ers came alive with last-minute theatrics before halftime, highlighted by Kittle’s 17-yard, third-down ...

The San Francisco 49ers fell short on the road, losing 26–15 to the Houston Texans. It was their worst defeat of the season, ...

In a 3-hour game, the San Francisco 49ers played about 10 minutes of good football as the Houston Texans dominated in every ...

Since its accidental inception in 2018, the fourth weekend of October has become a day of celebration. It began in Week 2 of ...

S Antoine Winfield Jr. recovers a fumble against the New Orleans Saints in Week 8 of the 2025 NFL season. OLB Anthony Nelson gets an interception return for a TD against the New Orleans Saints in Week ...

Just over a week ago, in Week 6 against the Tampa Bay Buccaneers, the San Francisco 49ers suffered a major blow when Fred ...