The San Francisco 49ers and the Arizona Cardinals square off in Week 3 of the NFL regular season today. Here's the start time and where to watch.

San Francisco 49ers vs Arizona Cardinals picks, predictions, odds, win probabilities for NFL Week 3 Sunday game on Sept. 21, 2025. Who will win today?

What channel is Arizona Cardinals vs San Francisco 49ers game on today? How to watch NFL Week 3 football game on TV, streaming Sunday, Sept. 21, 2025.

The NFL season continues with the Tampa Bay Buccaneers hosting the New York Jets Sunday. Start time, where to watch, streaming and NFL schedule.

The Sunday afternoon Cardinals vs. 49ers game will kick off at 4:25 p.m. ET on FOX. (Out-of-market fans can catch the game on ...

The San Francisco 49ers face the Arizona Cardinals on Sunday, Sept. 21, 2025 in Week 3 of the NFL season at State Farm ...

The San Francisco 49ers (2-0) host an NFC West showdown against the Arizona Cardinals (2-0) on Sunday, September 21, 2025 at ...

Happy gameday one and all. The Arizona Cardinals are taking on their division rival San Francisco 49ers this afternoon and it ...

How can I watch the Titans game today vs. Indianapolis Colts? TV channel, streaming info, NFL schedule in Week 3.

Here is everything you need to know about the San Francisco 49ers vs. Arizona Cardinals, including TV and streaming options for the Week 2 NFL game.

Learn which TV channel or how to live stream the NFL Week 3 San Francisco 49ers and Arizona Cardinals game, Sunday, Sept. 21.

The San Francisco 49ers have had a tough time with the Arizona Cardinals since head coach Kyle Shanahan took over in the 2017 season.