gut.bmj1d
Combining ferroptosis induction with MDSC blockade renders primary tumours and metastases in liver sensitive to immune checkpoint blockade
Objective Investigating the effect of ferroptosis in the tumour microenvironment to identify combinatory therapy for liver cancer treatment. Design Glutathione peroxidase 4 (GPx4), which is considered ...
gut.bmj8d
Localisation of PGK1 determines metabolic phenotype to balance metastasis and proliferation in patients with SMAD4-negative pancreatic cancer
Correspondence to Professor Xian-Jun Yu, Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, China; yuxianjun88{at}hotmail.com Design We combined molecular ...
gut.bmj7d
Dissecting transcriptional heterogeneity in primary gastric adenocarcinoma by single cell RNA sequencing
Objective Tumour heterogeneity represents a major obstacle to accurate diagnosis and treatment in gastric adenocarcinoma (GA). Here, we report a systematic transcriptional atlas to delineate molecular ...
gut.bmj6d
Kyoto international consensus report on anatomy, pathophysiology and clinical significance of the gastro-oesophageal junction
Objective An international meeting was organised to develop consensus on (1) the landmarks to define the gastro-oesophageal junction (GOJ), (2) the occurrence and pathophysiological significance of ...
gut.bmj8d
Cigarette smoke promotes colorectal cancer through modulation of gut microbiota and related metabolites
Correspondence to Professor Jun Yu, Institute of Digestive Disease, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China; ...
gut.bmj3d
The national colonoscopy audit: a nationwide assessment of the quality and safety of colonoscopy in the UK
2 Department of Gastroenterology, Gloucestershire Hospitals NHS Foundation Trust, Cheltenham General Hospital, Cheltenham, UK 3 Department of Gastroenterology, Gloucestershire Hospitals NHS Foundation ...
gut.bmj8d
PD-L1 blockade liberates intrinsic antitumourigenic properties of glycolytic macrophages in hepatocellular carcinoma
Objective Patients with increased PD-L1 + host cells in tumours are more potent to benefit from antiprogrammed death-1/programmed death ligand-1 (PD-L1) treatment, but the underlying mechanism is ...
gut.bmj11d
PSC-IBD: a unique form of inflammatory bowel disease associated with primary sclerosing cholangitis
1 Division of Gastroenterology and Hepatology, Mayo Clinic and Foundation, Rochester, MN, USA 2 Division of Biostatistics, Mayo Clinic and Foundation, Rochester, MN, USA Correspondence to: Dr E V ...
gut.bmj7d
UK guidelines for management of acute pancreatitis: is it time to change?
Department of General Surgery, Buckinghamshire Hospitals NHS Trust, Aylesbury, UK Correspondence to: MrK Gurusamy Department of General Surgery, Buckinghamshire Hospitals NHS Trust, 5 North Drive, ...
gut.bmj12d
Alternative treatments for type 2 diabetes and associated metabolic diseases: medical therapy or endoscopic duodenal mucosal remodelling?
Correspondence to Professor Jacques J G H M Bergman, Gastroenterology and Hepatology, Amsterdam UMC Location AMC, Amsterdam 1105 AZ, The Netherlands; j.j.bergman{at}amsterdamumc.nl Despite important ...
gut.bmj1d
IDDF2019-ABS-0025 Demographic profile and clinical presentation of IBD among inpatients seen from 2012–2018: a UERMMMC experience
Significance In the past, there has been a paucity of clinical and demographic information on inflammatory bowel disease in the Philippines. At the UERMMMMC, there was a growing trend for IBD ...