gut.bmj7d
Localisation of PGK1 determines metabolic phenotype to balance metastasis and proliferation in patients with SMAD4-negative pancreatic cancer
Correspondence to Professor Xian-Jun Yu, Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, China; yuxianjun88{at}hotmail.com Design We combined molecular ...
gut.bmj8d
Non-alcoholic fatty liver disease and increased risk of incident extrahepatic cancers: a meta-analysis of observational cohort studies
Objective We performed a meta-analysis of observational studies to quantify the magnitude of the association between non-alcoholic fatty liver disease (NAFLD) and risk of extrahepatic cancers. Design ...
gut.bmj7d
Dissecting transcriptional heterogeneity in primary gastric adenocarcinoma by single cell RNA sequencing
Objective Tumour heterogeneity represents a major obstacle to accurate diagnosis and treatment in gastric adenocarcinoma (GA). Here, we report a systematic transcriptional atlas to delineate molecular ...
gut.bmj3d
The national colonoscopy audit: a nationwide assessment of the quality and safety of colonoscopy in the UK
2 Department of Gastroenterology, Gloucestershire Hospitals NHS Foundation Trust, Cheltenham General Hospital, Cheltenham, UK 3 Department of Gastroenterology, Gloucestershire Hospitals NHS Foundation ...
gut.bmj5d
Kyoto international consensus report on anatomy, pathophysiology and clinical significance of the gastro-oesophageal junction
Objective An international meeting was organised to develop consensus on (1) the landmarks to define the gastro-oesophageal junction (GOJ), (2) the occurrence and pathophysiological significance of ...
gut.bmj1d
IDDF2019-ABS-0025 Demographic profile and clinical presentation of IBD among inpatients seen from 2012–2018: a UERMMMC experience
Significance In the past, there has been a paucity of clinical and demographic information on inflammatory bowel disease in the Philippines. At the UERMMMMC, there was a growing trend for IBD ...
gut.bmj8d
PD-L1 blockade liberates intrinsic antitumourigenic properties of glycolytic macrophages in hepatocellular carcinoma
Objective Patients with increased PD-L1 + host cells in tumours are more potent to benefit from antiprogrammed death-1/programmed death ligand-1 (PD-L1) treatment, but the underlying mechanism is ...
gut.bmj10d
PSC-IBD: a unique form of inflammatory bowel disease associated with primary sclerosing cholangitis
1 Division of Gastroenterology and Hepatology, Mayo Clinic and Foundation, Rochester, MN, USA 2 Division of Biostatistics, Mayo Clinic and Foundation, Rochester, MN, USA Correspondence to: Dr E V ...
gut.bmj7d
UK guidelines for management of acute pancreatitis: is it time to change?
Department of General Surgery, Buckinghamshire Hospitals NHS Trust, Aylesbury, UK Correspondence to: MrK Gurusamy Department of General Surgery, Buckinghamshire Hospitals NHS Trust, 5 North Drive, ...
gut.bmj13d
Butyrate inhibits inflammatory responses through NFκB inhibition: implications for Crohn's disease
Professor J P Galmiche, Centre de Recherche en Nutrition Humaine, CRI INSERM 95-08, CHU, Hôtel Dieu, Place A Ricordeau, 44035 Nantes cedex 01, France. Email:galmiche{at}easynet.fr BACKGROUND/AIM ...
gut.bmj13d
Targeting the gut-liver-immune axis to treat cirrhosis
Cirrhotic portal hypertension is characterised by development of the decompensating events of ascites, encephalopathy, portal hypertensive bleeding and hepatorenal syndrome, which arise in a setting ...
gut.bmj12d
Alternative treatments for type 2 diabetes and associated metabolic diseases: medical therapy or endoscopic duodenal mucosal remodelling?
Correspondence to Professor Jacques J G H M Bergman, Gastroenterology and Hepatology, Amsterdam UMC Location AMC, Amsterdam 1105 AZ, The Netherlands; j.j.bergman{at}amsterdamumc.nl Despite important ...