The San Francisco 49ers could completely flip their QB depth chart with Brock Purdy working through a toe injury.

Head coach Kyle Shanahan on Friday told reporters new starting left guard Connor Colby suffered a groin injury that will make him questionable for the 49ers' home opener Sunday vs. the Arizona ...

The San Francisco 49ers may have one of the best linebacker duos in the NFL today, and one of their legends recognizes it.

The San Francisco 49ers will take on the Arizona Cardinals this weekend. Here's what the experts think will happen on Sunday at Levi's Stadium ...

The San Francisco 49ers have stifled the run thanks to an impressive start for rookie defensive end Mykel Williams through two weeks.

The San Francisco 49ers may have to dig deep into their depth chart to find a starting left guard alongside Trent Williams in Week 3.

Brown, a third-round pick and the 49ers' first selection in the 2023 draft, was moved to the bench after starting 13 of the ...

San Francisco 49ers fans took over Caesars Superdome on Sunday against the New Orleans Saints, and Saints defensive end ...

The San Francisco 49ers badly need their rookie class to continue improving if they want to be Super Bowl contenders.

Some of the site's predictions differ from NFL Week 3 odds and other NFL Week 3 picks for NFL Week 3 games. How correct will ...

It sure looks like the San Francisco 49ers will have their starting quarterback for their Week 3 matchup with the Arizona Cardinals.

There's some good injury news for the San Francisco 49ers after their second Week 3 practice, but the Jauan Jennings update isn't great.