San Francisco 49ers defensive lineman Nick Bosa tore his ACL on Sunday against the Cardinals, and, per ESPN, requires season-ending surgery to repair it. Bosa, a five-time Pro Bowler, had already racked up 17 combined tackles in three games with the Niners in 2025. While the report is that the tear is clean, it still requires surgery to repair.

The SportsLine projection model has revealed its Baltimore vs. Detroit picks for the 2025 NFL Week 3 Monday Night Football game

Here is where the San Francisco 49ers sit in the NFL Week 4 power rankings after their thrilling win over the Arizona Cardinals.

Catch up on all the NFL action from week three as the Philadelphia Eagles and San Francisco 49ers claim late wins, while the Indianapolis Colts also remain unbeaten.

Jordan Love can still hold the Packers back, the Colts might be for real, and more in our weekly NFL Power Rankings.

One of the things that makes the NFL so much fun is that occasionally it takes the script for a week and sets it on fire.

The Texans turned the ball over three times with two interceptions thrown by C.J. Stroud. Travis Etienne scored a 10-yard game-winning rushing touchdown with 1:48 left in the game. Carson Wentz threw two touchdown passes and Jordan Mason rushed for 116 yards and two scores in a blowout win. Bengals quarterback Jake Browning was picked off twice.

Defensive contributions from the Philadelphia Eagles and Minnesota Vikings star in the best of the plays from week three of the NFL season.

NFL Week 3 was rife with close calls, comebacks and collapses, with the Cowboys defense among the groups giving off major warning signs.

Between clutch comebacks and three-touchdown performances, these players have already showcased why they could contend for the MVP trophy at the end of the regular season. The season is still very early,