The Arizona Cardinals have a pair of injured cornerbacks whose status is unknown for Sunday when they face the San Francisco 49ers. However, in what could be viewed as optimistic news, head coach Jonathan Gannon did not rule out any player for Week 3.

San Francisco is a 2.5-point favorite in the latest Cardinals vs. 49ers odds from SportsLine consensus, while the over/under for total points scored is 44.5. The 49ers are -128 money line favorites (risk $128 to win $100),

The Arizona Cardinals took their first loss of the season 16-15 against the 49ers as they hit a field with the clock hitting zero. The Los Angeles Chargers stayed undefeated after Cameron Dicker hit a

The Arizona Cardinals had three cornerbacks and a defensive lineman go down with injuries in the team's 27-22 Week 2 win over the Carolina Panthers. On Tuesday, they had three cornerbacks and a defensive lineman in for either tryouts or a visit, suggesting that at least one of the injured players won't be able to play this week.

The Arizona Cardinals and San Francisco 49ers both hope to emerge to 3-0 to begin the 2025 season, though the NFC West rivals stand in each other's way of doing just that on Sunday. Arizona is 2-0 for the first time since 2021 while the Niners have now done so in the last three-of-five seasons.