Vesicular protein transport and sorting between the intracellular compartments of the biosynthetic and secretory pathway and the compartments of the endocytic route starting at the plasma membrane ...

Osaka - Despite its less-than-stellar reputation in the news, cholesterol is an essential molecule for living things. It serves as the building block for hormones and helps give shape to the membranes ...

The Aster proteins (encoded by the Gramd1a-c genes) contain a ligand-binding fold structurally similar to a START domain and mediate nonvesicular plasma membrane (PM) to endoplasmic reticulum (ER) ...

Prof. Fang-Jen S. Lee's team at National Taiwan University has discovered that an intermediate cellular metabolism molecule, glycerol, regulates the localization and function of the Golgi protein Imh1 ...

Max Planck Institute of Molecular Cell Biology and Genetics led a study showing that directional, non-vesicular lipid transport drives fast, species-selective lipid sorting, outpacing slower, less ...

Intracellular transport of newly synthesized and mature proteins via vesicles is controlled by a large group of proteins. Here we describe a ubiquitous rat protein-endoplasmic reticulum (ER) and Golgi ...