Researchers from the University of Cologne and Heinrich Heine University Düsseldorf have identified a new ubiquitin form dedicated to proteostasis and healthy aging. They show that CxUb (C-terminally ...

Study reveals a ubiquitin precursor enhances cellular stress resistance and promotes longevity, offering new insights into ...

In response to cellular stress, the protein CxUb is activated to identify damaged proteins, thereby maintaining cellular health. The discovery could lead to ways to improve the treatment of cancer and ...

Several recent studies show that the E3 ligase RNF114 recognises a hybrid ADP-ribose-ubiquitin modification on substrate ...

Focusing on an enzyme in yeast, they demonstrated how contrasts in atomic scale motions impact their function. The method ...

When proteins within the body get tagged with a molecule called ubiquitin, they are essentially marked for destruction. But they can be saved; a deubiquitinase enzyme can remove the ubiquitin, keeping ...

Influenza viruses are becoming increasingly resilient to medicines. For this reason, new active ingredients are needed. Important findings in this regard have been provided: for the virus to ...

Preeclampsia is a pregnancy complication with serious risks for mother and child. The only real cure for preeclampsia is ...