Oxidative stress – characterized by elevated levels of unstable molecules called reactive oxygen species– is associated with neurodegeneration and cardiovascular disease. However, until recently it ...

In 2017, the number of monoclonal antibodies (mAbs) granted approval in the United States reached double-digits for the first time. Out of a total of 46 drugs approved by the US Food and Drug ...

Researchers in the United States and Canada have described the potential for a transgenic mouse model to serve as an effective platform for the study of severe acute respiratory syndrome coronavirus 2 ...

A "transgenic mouse," the first animal to be granted a patent by the U.S. Patent Office, rests on a hand in a laboratory at the Harvard Medical school on April 15, 1988, in Boston. AFP PHOTO VIN ...

Antibodies are a critical feature of the human adaptive immune response. New immunotherapies require the production of selective and non-autoimmunogenic antibodies. These engineered antibodies can ...

Plasmids comprising transgene insertions in four lines of transgenic mice have been retrieved by plasmid rescue into a set of Escherichia coli strains with mutations in different members of the ...

Last week, President Trump spoke for an hour and 40 minutes before a joint session of Congress to announce, among other things, that America was back. The nation's backness is too subjective to fact ...

This is a preview. Log in through your library . Abstract Sickle cell disease (SCD) is caused by a single point mutation in the human βA globin gene that results in the formation of an abnormal ...