Researchers identify a key pathway leading to neurodegeneration in early stages of ALS, hinting at the potential for short-circuiting the progression of the fatal disease if diagnosed early.

Degradation of motor neurons, conceptual computer illustration. Motor neuron diseases are a group of neurodegenerative disorders including amyotrophic lateral sclerosis, progressive bulbar palsy and ...

An experimental drug has successfully slowed the progress of amyotrophic lateral sclerosis in a phase 2 study, its developer announced on Tuesday. Participants taking AMX0035, designed to reduce ...

The onset of amyotrophic lateral sclerosis (ALS) is more common in adults over the age of 40 years. However, ALS may also occur in people in their 20s or 30s. ALS is a rare progressive ...

Amyotrophic lateral sclerosis (ALS), or Lou Gehrig disease, is a progressive, always-fatal neuromuscular disease characterized by motor neuron degeneration in the brain and spinal cord. As upper and ...

ALS is a progressive disease, meaning it worsens over time. Although there is no cure for ALS, medications and therapies are available to help manage the symptoms, slow the disease course, and prolong ...

Scientists invented a pocket-sized model of the most common form of amyotrophic lateral sclerosis (ALS). The "disease-on-a-chip," made using stem cells, could pave the way for new treatments for the ...

Neuroscientists at Macquarie University in Australia have developed a single-dose genetic medicine that has been proven to halt the progression of both ALS and frontotemporal dementia (FTD) in mice – ...

Approximately 5,000 people in the U.S. develop amyotrophic lateral sclerosis (ALS) each year. On average, they survive for only two to five years after being diagnosed, according to the Centers for ...