For much of nutrition science history, trace minerals were discussed almost exclusively in the context of deficiency diseases. Iodine prevented goiter, iron prevented anemia, and zinc supported growth ...

Study reveals that reversible chemical modifications can inhibit pyruvate kinase and affect its variants differently, ...

Hyperuricemia (HUA) is a metabolic disease caused by purine metabolism disorder, which is an important hub for many chronic ...

Enzymes originally evolved in high-temperature environments and later adapted to lower temperatures as Earth cooled. Scientists discovered that a key shift in enzyme function occurred over ...

Recent findings from a preclinical study conducted by Weill Cornell Medicine researchers have uncovered a pivotal role of the enzyme PGK1 in brain cell energy production, offering new hope for ...

Enzymes are proteins that facilitate biochemical reactions by acting as a catalyst, and thus, their expression and activity have a strong influence on the reactions taking place within cells. As ...

Liver diseases are commonly diagnosed using serum enzyme assays, particularly for aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma-glutamyl ...

A protein that has long frustrated diabetes researchers is suddenly at the center of a very different fight. By targeting an enzyme called protein tyrosine phosphatase 1B, or PTP1B, scientists are ...