Our food and our bodies are full of tiny protein fragments called peptides. These small chains of amino acids act as ...

The sequencing of the human genome has been a scientific landmark achievement, and it has had major implications for our understanding of human health 1. However, excluding contributing factors from ...

A new single-cell technology is giving scientists their clearest view yet of immune cell behavior—capturing not just genetic intent, but real-time activity. By measuring RNA and proteins ...

Despite advances in mass spectrometry and emerging single-molecule approaches, sequencing peptides at the single-molecule level remains a central challenge in proteomics. Here we present a ‘reverse ...

Proteins, one of the smallest building blocks of life on Earth, hold promise for answering some of biology's biggest questions. Consisting of amino acids strung together into peptide chains, these ...

Proteomics—a term first coined in the mid-1990s—refers to the study of the complete set of proteins expressed in a cell, tissue, or organism. In contrast to genomics and transcriptomics, proteomics is ...

D&D‑seq uses base editing to record DNA–protein interactions in single cells, enabling multiomics mapping of transcription ...

Textbooks often depict proteins in one conformation, but real life, as usual, is much messier. While some proteins have stable, unchanging structures, many others have intrinsically disordered regions ...

Proteins, one of the smallest building blocks of life on Earth, hold promise for answering some of biology’s biggest questions. Consisting of amino acids strung together into peptide chains, these ...