Automated platform optimizes enzyme production using cell-free protein synthesis and AI-driven design

Enzymes are essential to a wide range of industrial processes. As biocatalysts, they play a key role in producing active ...
Nature

Cell-Free Protein Synthesis Technologies articles from across Nature Portfolio

Protein binders that detect, activate, inhibit, or otherwise modulate their targets are pivotal for biomedical applications. With the increasing accuracy and accessibility of de novo protein design, ...
Nature

Cell-Free Protein Synthesis Technologies

Cell-free protein synthesis (CFPS) harnesses the molecular machinery of living cells in an open in vitro environment to produce proteins without the constraints of cell viability. Derived from crude ...
BIOENGINEER

E3 Ligase TRIP12 Drives Protein Synthesis and Tumour Growth Through mTOR Pathway

A new cell-line study reports that the E3 ubiquitin ligase TRIP12 promotes protein translation and tumour-like growth in ...

Evolutionary changes in key enzyme may help bacteria make proteins faster

Evolutionary changes in a key protein synthesis enzyme, isoleucyl-tRNA synthetase (IleRS), may help bacteria fine-tune how ...
GEN

Lactose-Eating Yeast Boosts Yields and Cuts Costs for Cell-Free Protein Synthesis

The yeast Kluyveromyces lactis (K. lactis) could become a highly productive, sustainable, cost-effective energy source for cell-free protein synthesis (CFPS) as biopharmaceutical manufacturers strive ...