NFL Week 1 Predictions

NFL Week 16 picks against spread

Chargers at Cowboys: Predictions, picks and odds for NFL Week 16 game

The Los Angeles Chargers (10-4) visit the Dallas Cowboys (6-7) at AT&T Stadium in Arlington for a Week 16 showdown, and USA TODAY's panel of NFL experts have locked in their picks and predictions for ...

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Week 16 NFL picks, odds, best bets from proven model: This 5-leg parlay pays nearly 25-1

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NFL Week 16 picks against the spread: Best ATS bets for all 16 games

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NFL 2025 Week 16 odds: Packers vs. Bears spread, line, over/under

Oddsmakers project a competitive contest between NFC North opponents when the Green Bay Packers (9-4-1) visit the Chicago Bears (10-4) on Saturday, December 20, 2025 at Soldier Field.

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Christian Watson injury update and status vs. the Bears in Week 16 | Dec. 20, 2025

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Packers vs. Bears prediction, pick, odds for Saturday's NFL Week 16 game - 12/20/2025

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Packers bold predictions for massive Week 16 clash with Bears

These teams will kick off at 8:20 p.m. (ET) on Saturday with the NFC North title likely on the line.

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Pro Picks: Rams, Bears and Panthers will win in first-place showdowns

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NFL Week 16 announcers, TV broadcasters, announcing crews this week

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NFL Week 16 picks: Bears, Panthers tighten grip on division races; Saints' Tyler Shough keeps rolling

Now, he's going up against a Jets defense that just allowed Trevor Lawrence to post six total touchdowns (five passing and one rushing), which led to the firing of defensive coordinator Steve Wilks. Shough shouldn't face much resistance this week, which could make it very hard for undrafted rookie Brady Cook to keep up in his second career start.

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NFL Week 16 picks: Rams defeat Seahawks; Broncos edge Jaguars

Sam Farmer makes his picks and score predictions for Week 16 of the NFL season, with the Rams sweeping the Seahawks and the Broncos extending their winning streak.

Eagles vs. Commanders preview Week 16

Here's everything you need to know when the Philadelphia Eagles play the Washington Commanders Week 16 of the 2025 NFL season.

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NFL predictions: NFC North race is wide open entering Week 16

According to the SportsLine Inside the Lines team's projection model, the battle for the division title is far from over with three weeks remaining in the 2025 NFL season

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Bold predictions for Steelers' Week 16 matchup vs. Lions

Here are a few bold predictions for the Pittsburgh Steelers' Week 16 matchup vs. the Detroit Lions this Sunday.

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Broncos and Jaguars clash in marquee Week 16 matchup with playoff implications on the line

Sunday, 4:05 p.m. EST, Fox. BetMGM NFL odds: Broncos by 3. Against the spread: Jaguars 9-5, Denver 6-7-1. Series record: Broncos lead 8-7, including 1-1 in the playoffs. Last meeting: Broncos beat the Jaguars 21-17 on Oct.