UFC 321 goes down Saturday with two highly anticipated championship fights atop the bill, and MMA Junkie Radio's "Gorgeous" George and "Goze" will host a live-streamed watch-along right here at 2 p.m. ET.

The stage is set for UFC 321, headlined by the heavyweight title bout between Tom Aspinall and Ciryl Gane on Saturday, Oct. 25, 2025 (10/25/25) at Etihad Arena in Abu Dhabi.

The UFC heads to the Etihad Arena in Abu Dhabi, United Arab Emirates tonight (October 25) for a stacked UFC 321 card featuring two championship fights.

In the US, the UFC Vegas 110 preliminary card and main card action will be available to watch and stream live from UFC Fight Pass and ESPN+ from 4:00 PM (ET) and 1:00 PM (PT).

Reminder: We will deliver live round-by-round, blow-by-blow coverage of UFC 321’s entire fight-fight pay-per-view (PPV) main card RIGHT HERE, beginning at 2 p.m. ET.

Date: Oct. 4 | Location: T-Mobile Arena -- Las Vegas Early prelims begin at 6 p.m. ET and can be seen on FX/ESPN+ Televised prelims begin at 8 pm. ET and can been seen on FX/ESPN+ Main card begins at 10 p.m. ET Watch live: ESPN+ PPV | Price: $79.99

And in the night’s headliner, a new era at strawweight is set to be ushered in, with Mackenzie Dern vying for the vacant title against Brazilian star Virna Jandiroba — with Zhang Weili set for a flyweight move next month at UFC 322.