Apelin is a multifunctional peptide that stimulates angiogenesis in a VEGF-A-dependent manner. A study now shows that apelin produced by intestinal endothelium drives VEGF-A-independent angiogenesis ...

Obesity is a modifiable risk factor in cancer development, especially for gastrointestinal cancer. While the etiology of colorectal cancer is well characterized by the adenoma-carcinoma sequence, it ...

In a recent study, FMI researchers have shed light on how intestinal organoids form crypts, the pockets that house stem cells for gut regeneration and long-term stability. Their findings may have ...

Intestinal epithelial cells line the inner wall of the gut, creating a barrier to dangerous bacteria like enteropathogenic E. coli that seek to attach and efface that barrier, causing diarrhea. Such ...

Your gut is a wondrous place. A special layer of cells that coats the insides of your small and large intestines takes in nutrients and water from what you ate while keeping anything bad out of your ...

The inner lining of the gut regenerates entirely every four to seven days, thanks to stem cells in the intestinal epithelium. Yet much remains shrouded in mystery regarding stem cells and what causes ...

Researchers at the University of Gothenburg have been studying the mucus involved in defending the intestines and airways against infection for more than 30 years. To date, their work has focused very ...

An international team of scientists based in the Netherlands, and in China, has found that intestinal cells can change specializations during their lives, driven by the BMP signaling pathway, an ...

Two independent studies by Columbia scientists suggest that research into the gut's stem cells over the past 15 years has been marred by a case of mistaken identity: Scientists have been studying the ...

To act as a robust barrier against pathogens while also absorbing needed nutrients, the lining of the intestines must regenerate on a daily basis to remain equal to the task. The intestine’s resident ...

Intestinal cells can change specializations during their lives. The BMP signaling pathway -- an important communication mechanism between cells -- appears to be the driver of these changes, according ...

Stem cells are a hot topic for creating medical treatments. However, scientists still do not fully understand how they choose to divide or differentiate to renew organs. Researchers have now found a ...