The e-Lung score is associated with mortality and a decline in FVC when applied to CT scans at baseline in patients with non-IPF ILD.
AI models suggest IPF is a dysregulation of aging, not just accelerated aging, with unique gene expression patterns. Key pathways in IPF and aging include TGF-β signaling, oxidative stress, ...
Not intended for UK and US audiences Nerandomilast long-term survival modeling presented at American Thoracic Society (ATS) 2026 and European ...
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SOUTH SAN FRANCISCO, Calif., March 03, 2025 (GLOBE NEWSWIRE) -- Pliant Therapeutics, Inc. (Nasdaq: PLRX) today announced that following a prespecified data review and recommendation by the trial's ...
Multiphoton microscopy can help quantify collagen signatures, thereby mapping the fibrotic microenvironment in idiopathic pulmonary fibrosis.
What is idiopathic pulmonary fibrosis (IPF)? Idiopathic pulmonary fibrosis (IPF) is a debilitating and fatal lung disease that affects approximately 3 million people worldwide. Despite the condition ...
Idiopathic pulmonary fibrosis (IPF) is a disease that causes scarring in the lungs. Eventually, the lungs can become so scarred that they can’t pull enough oxygen into the bloodstream. IPF is a ...
Antifibrotic treatments for IPF, such as pirfenidone and nintedanib, are associated with significant side effects impacting quality of life. Despite side effects, patients perceive antifibrotics as ...
If the research is successful, Simcere may in-license the molecule and obtain all global rights to the product.