Gram-positive bacteria show blue or purple after Gram-staining in a laboratory test. They have thick cell walls. Gram-negative bacteria show pink or red on staining and have thin walls. They release ...

Health care-associated infections are a common problem in suppurating wound care, as is the rise in multi-drug resistant bacteria. In order to effectively and selectively combat bacterial infections, ...

Researchers from the National University of Singapore (NUS) have solved a 60-year-old mystery in bacterial cell envelope biology, defining the primary function of an important protein complex ...

A team led by Paul Hergenrother at the University of Illinois Urbana-Champaign has discovered a new antibiotic that exclusively targets gram-negative bacteria and avoids wiping out the ecosystem of ...

Gram-negative meningitis is a form of meningitis. The term gram-negative refers to a way of differentiating bacteria. This type of bacteria is typically resistant to drugs and most available ...

Colistin, a polymyxin antibiotic rediscovered as a last-resort therapy against multidrug-resistant Gram-negative infections, exerts its bactericidal effect by binding to lipopolysaccharide (LPS) in ...

The Tol-Pal complex maintains bacterial outer membrane (OM) stability by regulating lipid homeostasis. (Left) In Gram-negative bacteria, the OM acts as a protective barrier, blocking entry of harmful ...

• Require X (hemin) and/or V (nicotinamide adenine dinucleotide) factors for growth • Responsible for 0.5–1% of all cases of IE • Haemophilus aphrophilus is the most common species responsible for IE ...

Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis, while sparing healthy microbes in the mouse ...