Human pluripotent stem cells (hPSCs) represent powerful tools for modelling early human embryogenesis and provide a source of differentiated cells for use in regenerative medicine. The assurance of ...

A Petri dish transforms into a canvas in Ph.D. student Hadley Hanson’s painting of macrophages engulfing cancer cells. (Santa Barbara, Calif.) — Scientists have solved a cellular murder mystery nearly ...

acid that is the genetic ingredient essential for life. In healthy cells, proteins manufacture DNA and remove or repair any broken strands. When proteins fail to repair damaged DNA, good cells may ...

Researchers at the Icahn School of Medicine at Mount Sinai have discovered how to reverse aging in blood-forming stem cells in mice by correcting defects in the stem cell's lysosomes. The breakthrough ...

G4 and R-loop signals at the indicated genomic locus. Both G4s and R-loops accumulate in cells where the resolution of G4 knots is defective (red). Not all DNA looks like the familiar twisted ladder.

Meghan McLean Poon Ph.D., Karen Potter Ph.D., Yuying You Ph.D. Cell and gene therapies represent a transformative frontier in modern medicine, offering potential cures for previously untreatable ...