Researchers engineered a CRISPR base editor to correct the ACTA2 mutation causing multisystemic smooth muscle dysfunction ...

Researchers engineered and screened dozens of base editors to precisely target a single mutation without editing other portions of the DNA.

Northwestern scientists have developed a new nanostructure that supercharges CRISPR’s ability to safely and efficiently enter cells, potentially unlocking its full power to treat genetic diseases. By ...

A new CRISPR-Cas toolkit, dubbed "pAblo·pCasso," is set to transform the landscape of bacterial genome editing, offering unprecedented precision and flexibility in genetic engineering. The new ...

Multisystemic smooth muscle dysfunction syndrome (MSMDS) is a rare condition associated with stroke, aortic dissection ...

This new patented toolbox, complementing - and for certain applications surpassing - CRISPR, is now available for researchers and industry in the field of genome engineering. The results are reported ...

Late-breaking data at the ESC Congress showcased the success of STX-1200, a novel CasXE-based therapy for durably lowering Lp(a). STX-1200 achieved unprecedented potency and specificity, with >90% ...

A Ph.D. student in biomolecular engineering at the University of California, Santa Cruz, has built a software program designed to facilitate the kind of precision genome editing involved in the ...

Unquestionably, we will emerge from this revolutionary period with modified views of components of cells and how they operate, but only, however, to await the emergence of the next revolutionary phase ...

On November 25, 2018, Chinese scientist He Jiankui made history as he genetically edited two embryos and implanted them into a woman’s uterus, the embryos later created real babies. Even more ...