Elongation is often interrupted by interactions between positively charged nascent polypeptides and negatively charged ribosomal RNA. Studies have found that in prokaryotic Escherichia coli cells, the ...

Elongation, a crucial step in the translation process of protein synthesis, gets disrupted by amino acid sequences with an abundance of N-terminal aspartic and glutamic acid residues in eukaryotic ...

This is a preview. Log in through your library . Abstract RNA polymerase II (Pol II) generally pauses at certain positions along gene bodies, thereby interrupting the transcription elongation process, ...

Transcriptional elongation involves the rapid extension of RNA chains by DNA-dependent RNA polymerases, but structural information on the mechanistic basis of this process has been lacking. Vassylyev ...

Proper chromosome segregation into two future daughter cells requires the mitotic spindle to elongate in anaphase. However, although some candidate proteins are implicated in this process, the ...

Researchers reveal a novel mechanism that coordinates the assembly of components inside cells that control gene expression. A team led by researchers at Baylor College of Medicine and the Czech ...

Fetal abnormalities are of concern to all prospective parents, and many of these problems originate from abnormalities in the development of the embryo particularly during its elongation and division.

This is a preview. Log in through your library . Abstract A microsomal fatty acid elongase activity measured in epidermis of rapidly expanding leek (Allium porrum L.) was 10-fold higher in specific ...

Life depends on the precise functioning of several proteins synthesized in cells by ribosomes. This diverse set of proteins, known as a proteome, is maintained by the robust translation elongation of ...