Understanding what depression is – and what it is not – is often the first step toward relief.

Depression-related fatigue is caused by cellular "overworking" at rest and a failure to produce energy under stress.

Researchers found that the cells of young adults with depression overproduce energy while resting but struggle to respond to ...

Hyperarousal plays an important role in mental disorders. It influences the severity of insomnia, depression, anxiety, ...

Researchers have discovered a surprising change in how cells produce energy in people with depression. Brain and blood cells in young adults with major depressive disorder produced more energy ...

The US Food and Drug Administration is allowing the use of Rejoyn, the first prescription digital treatment for major depressive disorder. Rejoyn, made by Otsuka Pharmaceutical and Click Therapeutics, ...

Imagine wading through severe depression for years, taking medication after medication, with no relief. Now, envision discovering that what you were facing was not major depression but bipolar ...

Dr.: There are well-established therapies that can help those afflicted with SAD to get through the dark winter months ...

Anti-inflammatory therapies that are highly effective for inflammatory skin diseases might also be relevant to depression ...

Diagnosing bipolar disorder can be difficult. While it is not hard to distinguish between its two characteristic phases—the high spirits of mania and the low spirits of depression—it is challenging to ...

Mental health professionals use the DSM to standardize the diagnosis and treatment processes for mental health conditions, including types of depression. The Diagnostic and Statistical Manual of ...

Cannabis use disorder has a bidirectional and clinically meaningful association with major depressive disorder, new research suggests.