Coupling reactions are among the most transformative tools in organic chemistry, enabling the formation of crucial chemical bonds in pharmaceuticals, agrochemicals, and advanced materials. Since their ...

Transition-metal-catalysed C–N coupling between aryl halides and amines is one of the most widely used methods for the synthesis of aniline-containing molecules in a range of industrial settings.

Using asymmetric catalysis to simultaneously form carbon–carbon bonds and generate single isomer products is strategically important. Suzuki-Miyaura cross-coupling is widely used in the academic and ...

Reactions that let chemists selectively make one enantiomer of a molecule over another fall into a field of modern organic chemistry called asymmetric catalysis. These reactions are crucial for ...

In an effort to open the door to new and useful products, chemistry researchers are on the continual lookout for processes ...

DIRECT CROSS-COUPLING of aryl halides with alkyl halides to form substituted aryl compounds—one of the most indispensable types of reactions in organic synthesis—has just gotten easier thanks to a new ...