New ultra-detailed imaging exposes the hidden structure and behavior of chromatin condensates — and hints at how their failures may drive disease.

Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and ...

There is a huge amount of DNA in most human cells, and that DNA has to be carefully compacted and organized so that it will ...

Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and ...

Study finds CRISPR/Cas gene editing causes “chromatin fatigue” – another surprise mechanism by which it can produce unwanted ...

A novel, freely available AI tool has cut the time it takes to determine chromatin structure from days to minutes. The 3D structure of DNA is important for controlling cell-specific gene expression ...

The developmental period is a critical window during which environmental cues interact with the genome to shape lifelong trajectories of health and disease.

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

Myelodysplastic syndrome (MDS) arises from defective blood stem cells that progressively lose their normal functions.